Sarkale, A. M.; Appayee, C. “Method for the asymmetric synthesis of (S)-paraconic acid”. Indian Patent, Application No. 201721019540, Filed on 3 June 2017.
Publications from IITGN
This paper was among the most downloaded articles by the readers of Organic Letters in the month of April 2019.
This work is highlighted in Synfacts 2019, 15, 0797.
Sarkale, A. M.; Kumar, A.; Appayee, C.* “Organocatalytic Approach for Short Asymmetric Synthesis of (R)-Paraconyl Alcohol: Application to the Total Syntheses of IM-2, SCB2, and A-Factor γ-Butyrolactone Autoregulators”. J. Org. Chem. 2018, 83, 4167-4172.
Kutwal, M. S.; Appayee, C.* “Front Cover: Highly Regio- and Enantioselective γ-Alkylation of Linear α,β-Unsaturated Aldehydes”. Eu. J. Org. Chem. 2017, 29.
Kutwal, M. S.; Appayee, C.* “Highly Regio- and Enantioselective γ-Alkylation of Linear α,β-Unsaturated Aldehydes”. Eu. J. Org. Chem. 2017, 4230-4234.
This article is featured in the virtual issue “Emerging Investigators from India”.
Publications from Postdoctoral and Doctoral Research
Appayee, C.; Breslow, R.* Deuterium studies reveal a new mechanism for the formose reaction involving hydride shifts. J. Am. Chem. Soc. 2014, 136, 3720–3723.
Chen, W.; Li, H.; Widowsky, J. R.; Appayee, C.; Venkataraman, L. Aromaticity decreases single-molecule junction conductance. J. Am. Chem. Soc. 2014, 136, 918–920.
Jones, J. H.; Appayee, C.; Brenner-Moyer, S. E.* One‐pot preparation of enantiopure fluorinated β‐amino acid precursors. Eur. J. Org. Chem. 2014, 5273–5280.
Breslow, R.*; Ramalingam, V.; Appayee, C. Catalysis of glyceraldehyde synthesis by primary or secondary amino acids under prebiotic conditions as a function of pH. Origins Life Evol. Biospheres 2013, 1–7.
Breslow, R*.; Appayee, C. Transketolase reaction under credible prebiotic conditions. Proc. Natl. Acad. Sci. USA 2013, 110, 4184–4187.
Appayee, C.; Fraboni, A. J.; Brenner-Moyer, S. E.* γ-Amino alcohols via organocascade reactions involving dienamine catalysis. J. Org. Chem. 2012, 77, 8828–8834.
Appayee, C.; Brenner-Moyer, S. E.* Organocatalytic enantioselective olefin aminofluorination. Org. Lett. 2010, 12, 3356–3359. (Highlighted in Synfacts, 2010, 9, 1070.)
Takenaka, N.; Sarangthem, R.; Chandrakumar, A. Helical chiral 2-aminopyridinium ions: A new class of hydrogen bond donor catalysts. J. Am. Chem. Soc. 2010, 132, 4536–4537. (Highlighted in Synfacts, 2010, 6, 0712.)
Prasad, K. R.*; Chandrakumar, A.; Dikundwar, A. G.; and Guru Row, T. N. Polymorphism in a TADDOL analogue induced by the presence of a chiral impurity. CrystEngComm 2010, 12, 3452–3454.
Prasad, K. R.*; Chandrakumar, A. Stereoselective synthesis of cytotoxic anhydrophytosphingosine pachastrissamine [jaspine B]. J. Org. Chem. 2007, 72, 6312–6315.
Prasad, K. R.*; Chandrakumar, A. Stereoselective syntheses of γ-alkyl (aryl)-α,β-dihydroxy-γ-butyrolactones and naturally occurring lipid guggultetrol. Tetrahedron, 2007, 63, 1798–1805.
Prasad, K. R.*; Chandrakumar, A.; Anbarasan, P. Asymmetric synthesis of both enantiomers of α-methyl-α-methoxyphenylacetic acid from L-(+)-tartaric acid: Formal enantioselective synthesis of insect pheromone (–)-frontalin. Tetrahedron: Asymmetry, 2006, 17, 1979–1984.
Prasad, K. R.*; Chandrakumar, A. Nucleophilic addition reactions of 1,4-diketones derived from tartaric acid: Synthesis of TADDOL analogues. Synthesis, 2006, 2159–2166.
Prasad, K. R.*; Chandrakumar, A. Asymmetric synthesis of α-methoxyarylacetic acid derivatives. Tetrahedron: Asymmetry, 2005, 16, 1897–1900.